Sanggenone C ( Sanggenone C; Sanggenon C )

Catalog No. M19128 CAS No. 80651-76-9

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Sanggenone C
Note

Research use only, not for human use.
Brief Description

Sanggenone C inhibits tumor cellular proteasomal activity and cell viability, via induction of cell cycle arrest and cell death , inhibiting the proteasome function.
Description

Sanggenone C inhibits tumor cellular proteasomal activity and cell viability, via induction of cell cycle arrest and cell death , inhibiting the proteasome function. Sanggenone C and O inhibited NO production and iNOS expression by suppressing NF-κB activity and IκBα activation; inhibited TNF-alpha -stimulated PMN-HSC adhesion and expression of VCAM-1 by suppressing the activation of NF-kappaB.
Synonyms

Sanggenone C; Sanggenon C
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

NF-κB
Research Area

——
Indication

——

CAS Number

80651-76-9
Formula Weight

708.71
Molecular Formula

C40H36O12
Purity

98%
Solubility

——
SMILES

CC1=CC(C(C(C1)C2=C(C=C(C=C2)O)O)C(=O)C3=C(C=C(C=C3)O)O)C4=C(C=C5C(=C4O)C(=O)C6(C(O5)(C7=C(O6)C=C(C=C7)O)CC=C(C)C)O)O
Chemical Name

2-((1S,2R,3S)-2-(2,4-dihydroxybenzoyl)-2',4'-dihydroxy-5-methyl-1,2,3,6-tetrahydro-[1,1'-biphenyl]-3-yl)-1,3,8,10a-tetrahydroxy-5a-(3-methylbut-2-en-1-yl)-5a,10a-dihydro-11H-benzofuro[3,2-b]chromen-11-one